Synergy BioNaturals Blog

Is ​Nano-Enhanced CBD​ Better For Me?

Posted by Thomas Crowhurst on 9/20/19 4:41 PM


A bottle of softgels tipped over with golden softgel capsules spilling on the table and a tincture bottle next to it with oil coming out of the dropper.



CBD is quickly becoming the go-to supplement for many individuals experiencing chronic pain, anxiety, and sleep issues. In a recent interview with People magazine, Kim Kardashian revealed that she uses CBD oil to relax and added: “I got into CBD a few months ago. It saved my life. I will use a little bit and fall asleep. I don’t think I would take a Xanax or an Ambien again.” 

The Many Forms of CBD


Different size bottles of CBD products like an oil tincture bottle and a full eyedropper next to it, softgels and the boxes they insert into.



CBD (cannabidiol) is the non-intoxicating compound produced in the flowers and leaves of Hemp and Cannabis.

Researchers studying the benefits of CBD have confirmed its therapeutic action in reducing the symptoms caused by stress, pain, and lack of sleep.

CBD can be taken in many forms:

  • Vape
  • Drink
  • Topical
  • Under the tongue (Sublingual)
  • Softgel


CBD is synonymous with oil tinctures and vaping because these are the best forms that increase the bioavailability of CBD in the body. Bioavailability describes how much of something we ingest is utilized by our cells.

According to recent studies, only 6-12% of CBD is absorbed and made “bioavailable” to the body following oral consumption. That means you swallowed 100% CBD, and only 6% made it to your cells.

Why Is CBD Difficult To Absorb?

CBD is fat-soluble, which means it’s more compatible with oils and other fatty substances. Fat-soluble compounds like CBD resist attaching to water molecules.

Anyone who's ever tried cleaning a greasy pan knows that water without soap has little effect on the oil. Up to 60% of the human body is water, including our nutrient delivery system.

To increase the bioavailability (how much reaches our cells) of the CBD, many companies sell oil tinctures. When CBD oil is dropped under the tongue, the CBD molecules absorb into the tissues of the oral cavity, which are rich in blood vessels. This method of ingestion allows the CBD to enter systemic circulation quickly.



A CGI of a human torso with an artery extended from the body full of red blood cells to depict the bloodstream.


Once in the bloodstream, the small percentage of CBD that’s absorbed has a better chance of reaching the fatty part of our cells to produce its therapeutic benefits–right?


Large molecules like CBD that pass into the bloodstream are vulnerable to degradation by immune cells. Another thing to consider with oil tinctures is the fact that only a small amount of CBD can fit into the tiny spaces of our oral cavity.

To recap:

  • CBD is fat-soluble (hydrophobic), meaning it’s incompatible with the hydrophilic (water-soluble) environment of the body’s nutrient delivery system.
  • Companies use oil tinctures to take advantage of the rich vein of blood vessels under the tongue.
  • Large molecules like CBD are vulnerable to degradation by immune cells once they reach systemic circulation.
  • Only a small amount of CBD that’s placed under the tongue (10%) absorbs into the body. The rest is eliminated (due to poor solubility).

A hand throwing US money into a metal trash bin


Stop Wasting Money On Oil Tinctures–Nanotechnology To The Rescue!

Nano refers to a molecule that is so small, you need powerful instruments like an electron microscope to see it. In the world of digestion, nanoparticles are smaller than a human cell and move effortlessly through the body to their target sites.

But that’s not the real magic of nanotechnology. Nano-CBD works better because the CBD that’s shrunk down to the nanoscale is made compatible with water.

That’s right.

An infographic on nano-CBD that visually communicates the absorbability of nano-enhanced CBD using an abstract human outline with an artery extended from the body and blood cells circulating amidst small nano-sized water droplets.

Once CBD is nano-enhanced, it’s able to dissolve in water and behave as though it’s a water-soluble molecule. Also, the immune system leaves the nano-enhanced CBD alone because it’s bound to phospholipids which are needed for the structure and maintenance of our cells.

Nano-CBD Works

Many industry experts predict that nano-enhanced CBD is the way of the future. Already companies with advanced delivery systems such as nano-CBD are receiving positive feedback from their customers.

Nanotechnology is a promising tool that will make it easier to consume CBD without the worry that only a small percentage is made available to your cells. The big question: how much nano-CBD can reach your cells intact? Based on studies showing the effectiveness of nanotechnology in medicine, it’s estimated that 90% of nano-CBD absorbs into the body.

Compared to regular CBD, nano-CBD provides 5 times the anti-stress, anti-inflammatory, and neuroprotective benefits!

Check out our nano-enhanced CBD line here.



Is CBD right for you? Take our quiz to find out now!

Topics: CBD, News, healthy sleep, Research, Anti-stress, bioavailability, Nano-CBD